What is the recommended inflation pressure range for the distal cuff of an ETT to prevent mucosal tissue damage?

The recommended inflation pressure range for the distal cuff of an endotracheal tube (ETT) to prevent mucosal tissue damage is 20-30 mmHg. This range is important because maintaining the pressure within this limit helps to ensure adequate ventilation while minimizing the risk of injuries to the tracheal mucosa. Excessive pressure can lead to ischemia and subsequent necrosis of the tissue, resulting in complications such as tracheal stenosis or cuff leak.

Staying within the 20-30 mmHg range also balances effective sealing of the airway to prevent aspiration and the airway pressure needed to ventilate the patient adequately. Monitoring cuff pressure is essential in clinical practice because pressures outside this recommendation can lead to significant adverse effects on airway integrity and patient safety.